Nitroglycerine and catecholamine actions on smooth muscle cells of the canine coronary artery.
نویسندگان
چکیده
منابع مشابه
Smooth Muscle of the Porcine Coronary Artery
To study the mechanism of vasodilation induced by 6-(3-dimethylaminopropionyl) forskolin (NKH477), a water-soluble forskolin derivative, its effects on the acetylcholine (ACh)-induced contraction of muscle strips of porcine coronary artery were examined. [Ca2"]1, isometric force, and cellular concentrations of cAMP and inositol 1,4,5-trisphosphate were measured. NKH477 (0.1-1.0 ,uM), isoprotere...
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Background and Purpose: Previous studies have suggested that bilirubin is a potential contributor to cerebral vasospasm. The purpose of this investigation was to determine whether bilirubin accrues in subarachnoid clot, whether its vasoconstrictive effect could involve a direct action on arterial smooth muscle cells, and, if so, whether bilirubin affects their Ca2+ uptake. Methods: Subarachnoid...
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O'Rourke MF, Taylor MG (1966) Vascular impedance of the femoral bed. Circ Res 18: 126-139 O'Rourke MF, Tavlor MG (1967) Input impedance of systemic circulation. CircRes 20: 365-380 O'Rourke MF, Blazek JV, Morrells CL Jr, Krovetz LJ (1968) Pressure wave transmission along the human aorta. Changes with age and in arterial degenerative disease. Circ Res 23: 567-579 Patel DJ, Greenfield JC Jr, Aust...
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AIMS The 3D geometry of individual vascular smooth muscle cells (VSMCs), which are essential for understanding the mechanical function of blood vessels, are currently not available. This paper introduces a new 3D segmentation algorithm to determine VSMC morphology and orientation. METHODS AND RESULTS A total of 112 VSMCs from six porcine coronary arteries were used in the analysis. A 3D semi-...
متن کاملEffects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells.
OBJECTIVE Secondary failure due to late restenosis continues to occur in 30-50% of individuals after PTCA. beta-Blockers play an important role in the treatment of CAD. The aim of this study was to investigate the effects of the new beta-blocker nebivolol on cell proliferation of human coronary smooth muscle cells (haCSMCs) and endothelial cells (haECs) in comparison to traditional beta-blocker...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1980
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1980.sp013502